Chief Investigators Group

Meet our chief investigators

Our Chief Investigators Group (CIG) keeps Benitec Biopharma at the cutting edge of RNAi science and its application to human disease.

These scientists, internationally renowned in the field of RNAi, head Benitec Biopharma’s various R&D programs. Their experience and skill ensure that our programs remain at the cutting edge of technology, and their rigour ensures that our progress is sustained.  The CIG meets twice a year to review progress of the programs and to provide scientific advice and input into each of the programs, ensuring that Benitec Biopharma’s portfolio advances with adherence to best scientific practice.

Our Chief Scientist, Dr Mick Graham, is Chairman of the CIG, whose other members follow.

Dr Ken Reed BSc MSc PhD FATSE

Dr Reed was the scientific founder of Benitec, whose gene silencing technology came from research conducted at the Queensland Agricultural Biotechnology Centre (QABC) and CSIRO. Dr Reed was the founding director of QABC and previously a co-founder of Advanced Breeding Technology Pty Ltd, the first company to commercialise the use of PCR. He was Deputy Chair of the inaugural Australian Biotechnology Advisory Council and served for many years on the Australian Government's Genetic Manipulation Advisory Committee and the Board of the Australian Genome Research Facility. Dr Reed is a Fellow of the Academy of Technological Sciences and Engineering.

 

Dr John J Rossi PhD

Dr. Rossi is the Lidow family Professor and Chair of the Division of Molecular Biology, Beckman Research Institute of the City of Hope, and Dean, Graduate School of Biological Sciences, Beckman Research Institute of the City of Hope, Duarte, California. Dr. Rossi received his doctoral training in genetics at the University of Connecticut in Storrs and postdoctoral training in molecular genetics at Brown University. His research has focused on RNA biology and clinical applications of small RNAs. His group was the first to demonstrate that hammerhead ribozymes could be used for inhibition of HIV replication. This research program led to two clinical trials in which ribozyme genes have been transduced into hematopoietic stem cells for autologous transplant in HIV infected individuals. He is the recipient of an NIH Merit award for his work on ribozymes and HIV. Work in the laboratory continues to focus upon mechanisms of small RNA mediated inhibition of gene expression and RNA based therapeutics, with recent emphasis on function and applications of RNA interference and expressed short hairpin RNAs for therapeutic treatment of HIV and cancers. He has published over 200 peer reviewed articles and numerous reviews and commentaries on RNAi based therapeutics.

Dr York Zhu PhD

Dr York Zhu, the founder of both Biomics and NT Omics Inc., has 20 years R&D and business experience. He started his industrial R&D career at Clontech Labs (1993) as an R&D Manager following several years as an academic in the Memorial Foundation in Nagoya, Japan (1987-1989). During his 6 years at Clontech, he was granted the Achievement Award for his R&D and management which played a significant role in the USD$200 million acquisition by BD. In 2000, Dr Zhu worked as Chief Technology Officer in Genemed R&D headquarters for 4 years, where he was an inventor on several patents and led the R&D team to develop a gene drug discovery technology platform. Then as Vice President and Chief Scientist of Zytogene (a spin-off of Genemed) he managed R&D operations to successfully develop over 200 new products for Zymed, which brought the company to a high market value and was acquired by Invitrogen. In 2005, D, Zhu founded NT Omics, and invented Entire siRNA targets (EsT) library technology which filled a gap in this field of high throughput siRNA screening.. In 2006 D. Zhu established Biomics in Nantong, China, where he now serves as CEO and Chairman. The Company is a leading player in RNAi in China.

Dr. Zhu undertook his Ph.D at the Medical School of Nagoya University (Japan,1989-1993), and his MS in Nantong University (1982-1985). During his career, Dr. Zhu has published more than 30 papers, held 3 patents andhas 6 more patents in the process of application.

Professor Maria Kavallaris BAppSci UTS, PhD UNSW

Professor Maria Kavallaris is Head of the Pharmacoproteomics Program at the Children’s Cancer Institute Australia, and holds a conjoint academic appointment in the Faculty of Medicine, University of New South Wales. Her research contributions are internationally regarded and include identifying the mechanisms of action and resistance to anticancer drugs that target cell division; discovering new cytoskeleton interactions in cancer; and the development of less toxic cancer therapies using nanotechnology. Her program's research contributions include the identification of novel mechanisms of resistance to anticancer agents that target key proteins involved in cell division in childhood cancer.

Professor Kavallaris is an NHMRC Senior Research Fellow and her research contributions have been recognised by international and national awards and prizes including an International Agency for Research on Cancer Fellowship, an American Association for Cancer Research Women in Cancer Research Award, National Health and Medical Research Council (NHMRC) Career Development Award, a Young Tall Poppy Award, and an Australian Museum Eureka Prize. She is regularly invited to speak and chair at international meetings. Professor has authored over 70 publications and her expertise is reflected in invitations to edit a book, contribute book chapters and review articles, including, Nature Reviews Cancer. She has served on numerous committees including the Program Committee for the Annual Meeting of the American Association for Cancer Research and on grant review panels. Professor Kavallaris serves on the Board of the Australian Institute for Policy and Science and has played a major role in advocating for medical research through public outreach and served as President of the Australian Society for Medical Research.

Professor George Dickson BSc, PhD

Professor Dickson is the director of the Institute of Biomedical and Life Science at the Royal Holloway, University of London, UK.

He is working on programs in the field of the molecular genetics and gene therapy of neuromuscular, cardiovascular and neurodegenerative diseases. His research program involves development of gene therapeutics (lentiviral, adenoviral, adeno-associated virus, non-viral lipoplex vectors, oligonucleotide-based pharmaceuticals), use of transgenic animals and the understanding of signalling pathways in relation to the pathophysiology and treatment of the muscular dystrophies, atherosclerosis and hyperlipidaemia, and neurodegenerative disease. The work is supported by the European Union, Medical Research Council, Wellcome Trust, Muscular Dystrophy Campaign, British Heart Foundation, Wyeth Discovery, Gates Foundation, Glaxo-SmithKline, Association Francais contre les Myopathies, and the Muscular Dystrophy Association.

Dr Geoff Symonds, PhD

Dr Symonds is Chief Scientific Officer of Calimmune Inc and has a Conjoint Professor appointment at the University of New South Wales.

He is working on cell-delivered gene therapy for HIV/AIDS. The approach involves modifying hematopoietic stem cells and CD4+ T lymphocytes with anti-HIV genes and then re-introducing these cells to the individual to impact on CD4+ T cell count and HIV viral load. The anti-HIV genes are introduced with a self-inactivating lentiviral vector.  Dr Symonds has an extensive background in this area as well as research on the molecular basis for solid tumours and leukaemia. His HIV gene therapy clinical development work in Australia is supported by Calimmune, and grants from the Australian Research Council and Research Infrastructure Support Services.


 

 
 Technology
 Intellectual Property
 Pipeline & Partners
 Corporate
 Investors
  News
 

Benitec Biopharma Ltd, 1-15 Barr St Balmain (Sydney) NSW Australia             P.+ 61 (0) 2 9555 6986           E. info@benitec.com

 
Copyright © 2013 Benitec Ltd. All rights reserved.              Other Policies | Privacy               Home | Sitemap | Stock Info | Contact